Effectiveness of neoadjuvant chemotherapy in downstaging HER2+ and triple negative breast cancers.
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Authors
Bennet, Jessica
Youssef, Magdi
Townend, Alice
Issue Date
2023
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Abstract
Introduction: Neoadjuvant chemotherapy (NAC) is the administration of chemotherapy prior to surgical intervention, with the goal of downstaging of tumours to improve surgical outcomes or provide the option for breast conserving surgery where otherwise not possible. Triple negative breast cancer (TNBC), characterized by the lack of oestrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2) and HER2+ cancers are known to respond well to NAC.
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Citation
Lagore, M., Bennet, J., Youssef, M. and Townend, A. (2023) Effectiveness of neoadjuvant chemotherapy in downstaging HER2+ and triple negative breast cancers. European Journal of Surgical Oncology; 49 (5) : e227.
Publisher
European Journal of Surgical Oncology
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ISSN
0748-7983