DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC).
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Authors
Bradburn, Mike
Kelly, Seamus
Issue Date
2010
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Abstract
Epigenetic marking such as DNA methylation influence gene transcription and chromosomal stability and may also be affected by environmental exposures. Few studies exist on alteration in DNA methylation profiles (genomic and gene specific methylation) in patients with Ulcerative Colitis (UC) and none assessing its relationship with lifestyle exposures.
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Citation
Arasaradnam, P., Khoo, K., Bradburn, M. et al. (2010) DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC). Epigenetics; 5 (5) : 422-426.
Publisher
Epigenetics
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Issue
PubMed ID
ISSN
1559-2308